Finely crushed seeds 100 mg/kg or 250 mg/kg of body weight of Securigera Securidaca or their extracts with petroleum ether, absolute ether or chloroform 100 mg/kg of body weight were administered to albino mice to study their effects on brain excitability. The drugs significantly increased minimal electroshock-brain seizure-threshold. This effect might be due to increase the brain concentration of γ-aminoburyric acid.
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Al‐Hachim et al. (1969) studied this question.