MALIGN: A Multiple Sequence Alignment Program

MALIGN is a computer program that aligns molecular sequences in a phylogenetic context. Although the program is designed around the analysis of nucleic acid sequence data, proteins can be aligned through conversion to nucleotide ambiguities The program produces sequence alignments that will yield parsimonious phylogenetic reconstructions MALIGN provides a number of heuristic and exact procedures (analogous to those used in phylogenetic reconstruction programs) to align the sequences and yields alignments in a vanety of formats suitable for direct input into other programs MALIGN is available for DOS, DOS-386, Macintosh, and SUN Unix Workstations The program will also operate in DOS windows provided by MS-Windows or OS2