Pulmonary Alveolar Proteinosis

Article1 September 1965Pulmonary Alveolar ProteinosisEndobronchial TreatmentJOSE RAMIREZ-R., M.D., GUY D. CAMPBELL, M.D., F.A.C.P.JOSE RAMIREZ-R., M.D.Search for more papers by this author, GUY D. CAMPBELL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-3-429 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPulmonary alveolar proteinosis is characterized pathologically by the accumulation of a lipid-rich proteinaceous material within the alveolar spaces in the absence of an inflammatory response (1). The striking roentgenographic feature is a changing pattern of acinar infiltrates that may involve any lobe but that is frequently more apparent in the central areas of the lung (2). There is no characteristic clinical pattern to the disorder. Symptoms and findings result from a progressive impairment of gas exchange or are a sequel to complicating bacterial or fungal infections. In some cases, an active pulmonary injury is suggested by persistently elevated serum levels...References1. ROSENCASTLEMANLIEBOW SHBAA: Pulmonary alveolar proteinosis. New Eng. J. Med. 258: 1123, 1958. CrossrefMedlineGoogle Scholar2. RAMIREZ-R. J: Pulmonary alveolar proteinosis: A roentgenologic analysis. Amer. J. Roentgen. 92: 571, 1964. Google Scholar3. RAMIREZ-R.NYKAMCLAUGHLIN JWJ: Pulmonary alveolar proteinosis: diagnostic technics and observations. New Eng. J. Med. 268: 165, 1963. CrossrefMedlineGoogle Scholar4. RAMIREZ-R. J: Pulmonary alveolar proteinosis, in Biochemical Clinics, No. 4: The Lung, edited by KUGELMASS, I. N. The Reuben H. Donnelley Corp., New York, 1964, p. 165. Google Scholar5. RAMIREZ-R.SCHULTZDUTTON JRBRE: Pulmonary alveolar proteinosis: a new technique and rationale for treatment. Arch. Intern. Med. (Chicago) 112: 419, 1963. CrossrefMedlineGoogle Scholar6. MCLAUGHLINRAMIREZ-R. JSJ: Pulmonary alveolar proteinosis: treatment by pulmonary segmental flooding. Amer. Rev. Resp. Dis. 89: 745, 1964. MedlineGoogle Scholar7. HENKINBISHOP RIHA: Pulmonary clearance of radioactive iodinated serum albumin in man. J. Lab. Clin. Med. 60: 709, 1962. MedlineGoogle Scholar8. TOIGOIMARISIOMURMALLLEPPER AJJHMH: Clearance of large carbon particles from the human tracheobronchial tree. Amer. Rev. Resp. Dis. 87: 487, 1963. CrossrefMedlineGoogle Scholar9. SHEFFNERMEDLERJACOBSSARETT ALEMLWHP: The in vitro reduction in viscosity of human tracheobronchial secretion by acetylcysteine. Amer. Rev. Resp. Dis. 90: 721, 1964. MedlineGoogle Scholar10. ANDRIOLEBALLASWILSON VTMGL: The association of nocardiosis and pulmonary alveolar proteinosis: a case study. Ann. Intern. Med. 60: 266, 1964. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOSE RAMIREZ-R., M.D.; GUY D. CAMPBELL, M.D., F.A.C.P.From the Medical Services of the Veterans Administration Hospital, Baltimore, Md., and Veterans Administration Center, Jackson, Miss.Requests for reprints should be addressed to Jose Ramirez-R., M.D., Veterans Administration Hospital, 3900 Loch Raven Blvd. Baltimore, Md. 21218. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUnilateral Presentation of Pulmonary Alveolar ProteinosisOne-session bilateral sequential whole lung lavage (OSBSWLL) for the management of pulmonary alveolar proteinosis"Crazy-paving" pattern: A characteristic presentation of pulmonary alveolar proteinosis and a review of the literature from IndiaPulmonary alveolar proteinosis: time to shift?Pulmonary Alveolar ProteinosisLa protéinose alvéolaire pulmonaireLipoprotéinose alvéolaire pulmonaireMaladies interstitielles pulmonairesAutoimmune Pulmonary Alveolar ProteinosisLa lipoprotéinose alvéolaire (LPA) en 2008Pulmonary alveolar proteinosisThis page intentionally left blankPulmonary Alveolar ProteinosisPulmonary Alveolar ProteinosisAlveolar proteinosis treated with a single bronchial lavageBronchopulmonary Lavage to Remove Pulmonary Casts and PlugsBronchoalveoläre Spülung zur Therapie der AlveolarproteinoseSekundäre maligne Tumoren der Bronchien und LungenBronchopulmonary Lavage: A “New” Approach to Old ProblemsPulmonary alveolar proteinosisPulmonary alveolar proteinosisBeitrag zur Alveolarproteinose der LungenMucociliary ActivityTracheobronchial LavageBronchopulmonary Lavage in ManJOSE RAMIREZ-R., M.D., RICHARD F. KIEFFER JR., M.D., WILMOT C. BALL JR., M.D. 1 September 1965Volume 63, Issue 3Page: 429-441KeywordsDehydrogenasesLactic acidLungsMedical servicesPathogensProteinsSerum albumin ePublished: 1 December 2008 Issue Published: 1 September 1965 PDF downloadLoading ...