Why the study?
Many hospitalized patients with acquired long QT syndrome are cancer patients, but their risk factors and clinical outcomes remained to be determined.
Does severe acquired long QT syndrome increase all-cause mortality in hospitalized cancer patients?
Population
150 hospitalized cancer patients with severe ALQTS and 293 matched controls from a cohort of 10,180
Comparison
Severe ALQTS (QTc ≥ 500 ms) vs age-, sex- and cancer-type-matched controls
Design
Matched case-control study within a cohort
Follow-up
Up to 2 years
Authors
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ALQTS was associated with higher mortality in hospitalized cancer patients; hypothesis-generating for prospective studies on QT monitoring.
Does severe acquired long QT syndrome increase all-cause mortality in hospitalized cancer patients?
Severe acquired long QT syndrome is present in 1.5% of hospitalized cancer patients and is associated with significantly higher all-cause mortality.
Lin et al. (2020) studied this question.
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