Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The human alpha subunit glycoprotein hormone gene utilizes a unique CCAAT binding factor.1990 · 63 citations
2. 2The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes.1992 · 167 citations
3. 3Identification of a Pancreatic β-Cell Insulin Gene Transcription Factor That Binds to and Appears To Activate Cell-Type-Specific Expression: Its Possible Relationship to Other Cellular Factors That Bind to a Common Insulin Gene Sequence1990 · 93 citations
4. 4<i>Drosophila</i> Nuclear Proteins Bind to Regions of Alternating C and T Residues in Gene Promoters1989 · 202 citations
5. 5Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei1983 · 11,637 citations