Genetic studies of single gene mutations are revealing mechanisms and pathways that regulate longevity across distant species ([1][1]). One such mechanism is an alteration in histone deacetylase activity. Abolishing expression of the Rpd3 deacetylase ([2][2]) or increasing expression of the Sir2
No takes yet. Share an insight, caveat, or question.
Rogina et al. (2002) studied this question.