July 1, 1968Canadian Journal of Physiology and Pharmacology

Compartments of sodium in a small artery

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Population

Viable tail artery samples

Design

Preclinical

Authors

SFSydney M. FriedmanUniversity of British Columbia BGBrigid Gustafson DHDorothy HamiltonDalhousie University

Discussion

Member takes

Implication

Preclinical differentiation of arterial Na pools warrants caution in humans; leaves open translation to vascular physiology or hypertension.

Structured PICO

Population

Viable tail artery samples

Intervention

Cooling and rewarming in a modified Krebs medium or Tris-buffered medium, and exposure to a sodium-free environment

Outcome

Sodium (Na) and potassium (K) exchange and mobilizationsurrogate

This preclinical study differentiates between metabolism-dependent cellular sodium and paracellular sodium in small arteries based on their mobilization kinetics during cooling and exposure to sodium-free environments.

Cite This Study

Friedman et al. (1968) studied this question.

synapsesocial.com/papers/6a8388b3daf812a7fbcd7dee https://doi.org/10.1139/y68-100

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Implication

Preclinical differentiation of arterial Na pools warrants caution in humans; leaves open translation to vascular physiology or hypertension.

Compartments of sodium in a small artery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Compartments of sodium in a small artery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider