Population
Patients with renal disease or renal failure
Design
Review
Authors
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Supports hypothesis generation on novel renal risks and pathways; leaves open whether targeting them alters cardio-renal outcomes.
This review highlights emerging risk factors and pathomechanisms, such as the sympathetic nervous system and endothelin system, driving the progression of renal disease.
Gross et al. (2004) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: