Construction and evaluation of platelet concentrate/mesoporous bioactive glass composite scaffolds for bone repair: injectable platelet-rich fibrin (i-PRF) vs. concentrated growth factors (CGF)

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preparation process of i-PRF-composited scaffolds resulted in higher retention of active components, while the complex extraction and preparation of gpCGF might have compromised its bioactivity. This study highlights the potential of i-PRF/MBG composite scaffolds in enhancing bone regeneration and suggests that i-PRF, with its higher concentration of bioactive factors and feasibility of compositing with scaffolds, offered an economically efficient solution for clinical bone repair, providing new insights for the development of future orthopedic biomaterials.