December 9, 2003Journal of Clinical Gastroenterology

Autonomic Dysfunction and Gastroparesis in Cirrhosis

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Population

30 patients, comprising 20 with cirrhosis of the liver and postprandial abdominal pain, nausea, and…

Design

Cohort

Authors

GVG. Nicholas VerneUniversity of Tennessee Health Science Center CSConsuelo Soldevia-PicoMedical University of South Carolina MRMichael E. RobinsonUniversity of Florida Health

Discussion

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Implication

Autonomic dysfunction may underlie delayed gastric emptying in cirrhosis; hypothesis-generating and requires prospective confirmation.

Structured PICO

Population

30 patients, comprising 20 with cirrhosis of the liver and postprandial abdominal pain, nausea, and vomiting, and 10 asymptomatic patients with Hepatitis C (HCV) and no evidence of cirrhosis.

Comparator

10 asymptomatic patients with Hepatitis C (HCV) and no evidence of cirrhosis.

Outcome

Gastric retention at 100 minutes (measured via solid phase gastric emptying study) and composite autonomic score (based on 5 standardized cardiovascular tests).surrogate

In patients with cirrhosis, autonomic dysfunction is significantly associated with delayed gastric emptying, which may explain their gastrointestinal symptoms.

Cite This Study

Verne et al. (2003) studied this question.

synapsesocial.com/papers/6a83a80020cfb2932ffe1938 https://doi.org/10.1097/00004836-200401000-00015

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Autonomic Dysfunction and Gastroparesis in Cirrhosis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Autonomic Dysfunction and Gastroparesis in Cirrhosis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider