Giant Follicular Lymphoma of the Stomach – Report of 4 Cases –

Four cases of primary giant follicular lymphoma of the stomach are reported. All patients were males and their ages were 53, 63, 66 and 71 years, respectively. Macroscoplcally, they were divided into 2 cases of ulcerative type, 1 case of polypoid type with hypertrophied rugae and 1 case of diffuse infiltrative type. One case transformed to the diffuse type of lymphosarcoma and died 9 months after gastrectomy. Giant follicular lymphoma could be differentiated from reactive lymphoid hyperplasia, based on the following histological features; uniformity of cellular composition, loss of lymphocytic rim, fusion of follicles, cellular atypism, and lack of phagocytosis and mixed inflammatory infiltrates.