Why the study?
Do lengthening contractions compared to shortening contractions induce different gene expression responses in the skeletal muscle of healthy young men?
Population
5 healthy young men
Comparison
Lengthening contractions performed with one leg vs Shortening contractions performed with the…
Design
Other
Follow-up
24 hours
Authors
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May inform contraction-specific training to optimize hypertrophy; leaves open mechanistic validation and clinical application.
Do lengthening contractions compared to shortening contractions induce different gene expression responses in the skeletal muscle of healthy young men?
Lengthening and shortening contractions activate distinct molecular pathways in human skeletal muscle as early as 3 hours post-exercise, which may explain differences in muscle hypertrophy.
Kostek et al. (2007) studied this question.
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