December 22, 2010Pain

High-resolution functional magnetic resonance imaging mapping of noxious heat and tactile activations along the central sulcus in New World monkeys

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Population

Anesthetized squirrel monkeys

Design

Preclinical

Authors

LCLi M. ChenVanderbilt University FWFeng WangVanderbilt University Medical Center RFRobert M. FriedmanOregon National Primate Research Center

Discussion

Member takes

Implication

Delineates segregated nociceptive processing in primate S1/M1; leaves open translation to human pain imaging and therapies.

Structured PICO

Population

Anesthetized squirrel monkeys

Intervention

Noxious heat (47.5°C) and tactile stimulation of digits

Outcome

Blood oxygen level-dependent (BOLD) fMRI activations at 9.4T in cortical areas around the central sulcussurrogate

High-resolution fMRI in monkeys demonstrates that multiple subregions of the primary somatosensory cortex and M1 are differentially engaged in processing noxious heat stimuli.

Cite This Study

Chen et al. (2010) studied this question.

synapsesocial.com/papers/6a83baea3fd01c19a6c579e8 https://doi.org/10.1016/j.pain.2010.10.048

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High-resolution functional magnetic resonance imaging mapping of noxious heat and tactile activations along the central sulcus in New World monkeys

Discussion

Member takes

Implication

Structured PICO

Cite This Study

High-resolution functional magnetic resonance imaging mapping of noxious heat and tactile activations along the central sulcus in New World monkeys

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider