Why the study?
Does dabigatran provide safe and effective thromboprophylaxis compared to standard of care in patients at risk of thromboembolism?
Population
Patients at risk of thromboembolic disease, including those undergoing orthopedic surgery and those with…
Comparison
Dabigatran etexilate vs Standard of care
Design
Review
Authors
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Supports dabigatran consideration for thromboprophylaxis; leaves open need for contemporary randomized comparisons.
Does dabigatran provide safe and effective thromboprophylaxis compared to standard of care in patients at risk of thromboembolism?
Dabigatran is the first in a new class of oral direct thrombin inhibitors licensed worldwide for thromboembolism prevention in orthopedic surgery and stroke prevention in atrial fibrillation.
Ryn et al. (2013) studied this question.
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