MIL-53(Fe/Ti)-NH2-loaded nanofibers for photodegradation of DOX and 5-FU during visible light/PMS activation

In the present study, MIL-53(Fe/Ti)-NH 2 bimetallic metal-organic frameworks (BMOFs) were incorporated into the polyacrylonitrile (PAN)/chitosan nanofibers. The functionality of the nanofibrous photocatalytic membrane was assessed as a peroxymonosulfate (PMS) activator to remove doxorubicin hydrochloride (DOX) and 5-fluorouracil (5-FU) from water. The photoluminescence spectra and transient photocurrent responses of the MIL-53 (Fe)-NH 2 MOFs and MIL-53 (Fe, Ti)-NH 2 BMOFs displayed a more efficient separation of photo-generated electron-hole pairs of MIL-53 (Fe, Ti)-NH 2 BMOFs. The BMOFs content of 4 wt%, pH of 7, and 2 mM PMS were optimal values for photocatalytic degradation of DOX and 5-FU using BMOFs-loaded nanofibrous membrane. The membrane composed of 4 wt% BMOFs attained the most effective degradation, resulting in the breakdown of 78.7% of the DOX and 81.2% of the 5-FU within 1 h. Upon the introduction of PMS and visible light irradiation, the permeation flux and rejection rate using 4 wt% BMOFs-loaded nanofibrous membrane for 5-FU and DOX increased, reaching 214.8 L.m −2 h −1 Bar −1 and 91.3% for DOX solution and 227.2 L.m −2 h −1 Bar −1 and 94.7% for 5-FU solution, after 1 h. The notable characteristics of the PAN/chitosan/MIL-53 (Fe, Ti)-NH 2 photocatalytic membrane, proved its effectiveness in the photodegradation of anticancer pharmaceuticals in water.