Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 19, 2019ACS Chemical BiologyOpen Access

Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants

View Full Paper
Ask AI
Bookmark
Share

Authors

STSean T. ToenjesVGValeria GarciaSMSean M. Maddox

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Toenjes et al. (2019) studied this question.

synapsesocial.com/papers/6a83c4798dcee831255bcefdhttps://doi.org/10.1021/acschembio.9b00407
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Protein Kinase Complement of the Human Genome2002 · 8,259 citations
  2. 2The promise and peril of chemical probes2015 · 864 citations
  3. 3Structural Bioinformatics-Based Design of Selective, Irreversible Kinase Inhibitors2005 · 514 citations
  4. 4Developing Irreversible Inhibitors of the Protein Kinase Cysteinome2013 · 676 citations
  5. 5Mechanisms of drug resistance in kinases2011 · 186 citations