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Early concepts of transport suggested that enzymes and transporters are evolutionarily related.In this brief minireview, evidence is presented suggesting that, contrary to this view, transport proteins and enzymes evolved independently of each other as two distinct classes of proteins from different precursor peptides.Transport systems probably evolved increasing degrees of complexity via the following pathway: channels 3 secondary carriers 3 primary carriers and group translocators.
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Milton H. Saier (2000) studied this question.
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