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August 1, 1988Journal of Biological ChemistryOpen Access

One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity.

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Authors

LPLars C. PetersenRoskilde UniversityLLLeif R. LundUniversity of Southern DenmarkLNLene NielsenIT University of Copenhagen

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Petersen et al. (1988) studied this question.

synapsesocial.com/papers/6a83d555b512e16c035bcd2chttps://doi.org/10.1016/s0021-9258(18)37940-7
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Activation of plasminogen by single-chain urokinase or by two-chain urokinase--a demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase)1987 · 136 citations
  2. 2Binding of single-chain prourokinase to the urokinase receptor of human U937 cells.1986 · 187 citations