Why the study?
Does the addition of pentoxifylline to ARB therapy reduce albuminuria in normotensive patients with type 2 diabetes and diabetic nephropathy?
Population
61 normotensive patients with type 2 diabetes, diabetic nephropathy, and residual albuminuria despite…
Comparison
Pentoxifylline 1200 mg daily added to ARB… vs Control group.
Design
RCT, randomly assigned
Follow-up
4 months
Authors
Loading...
Supports adjunctive pentoxifylline for albuminuria reduction beyond ARB in type 2 diabetic nephropathy; extends evidence for anti-inflammatory add-on therapy.
Does the addition of pentoxifylline to ARB therapy reduce albuminuria in normotensive patients with type 2 diabetes and diabetic nephropathy?
Adding pentoxifylline to ARB therapy significantly reduces albuminuria and TNF-alpha levels in patients with type 2 diabetes and diabetic nephropathy.
Navarro‐González et al. (2005) studied this question.