Why the study?
Does the presence of proteinuria increase cardiovascular mortality and cardiovascular risk factors in patients with type I diabetes?
Does the presence of proteinuria increase cardiovascular mortality and cardiovascular risk factors in patients with type I diabetes?
Proteinuria in type I diabetic patients is associated with significantly elevated cardiovascular risk factors (blood pressure, cholesterol, fibrinogen, platelet adhesion) and increased long-term cardiovascular mortality.
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Proteinuria may warrant closer CV monitoring in type 1 diabetes; extends long-term observational links but leaves causal effects open.
Valdorf-Hansen et al. (1987) studied this question.
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