Inactivation of plasminogen activators appeared to follow first‐order kinetics in the temperature range tested. The Arrhenius plot was linear (correlation coefficient 0.990). The Arrhenius equation for heat inactivation was deduced, from which the rate of inactivation at any temperature in the range 60–140°C could be calculated. The decimal reduction time (D‐value) was 109 min at 70°C and 32 set at 140°C. This indicated that native plasminogen activators in bovine milk are not affected by pasteurization, and to a large extent are not inactivated by UHT dairy processing conditions.
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Lu et al. (1993) studied this question.
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