Why the study?
Primary breast angiosarcoma is a rare neoplasm, especially in patients under 20 years old, and carries a poor prognosis due to a high relapse rate after surgical resection.
Highlights the possibility of late recurrence (>5 years) of primary breast angiosarcoma in young patients, emphasizing the need for long-term follow-up.
May warrant extended surveillance beyond 5 years in breast angiosarcoma; leaves open optimal follow-up duration and risk factors.
BACKGROUND: Primary breast angiosarcoma is a rare neoplasm; breast angiosarcoma patients under 20 years old are extremely rare. The prognosis is often poor due to a high relapse rate after surgical resection. CASE REPORT: We report on a case of a 17-year-old woman suffering from a primary breast angiosarcoma, associated with the local recurrence of a right-breast angiosarcoma 86 months after mastectomy. She received extensive local excision and transplantation of an adjacent skin flap. The post-operation diagnosis was angiosarcoma of histological grade III. CONCLUSIONS: This is a rare case as the patient was below 18 years old and the follow-up was greater than 5 years. Taken together, long-term close follow-up is extremely important, regardless of how long after surgery and the status of the surgical margins.
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Wu et al. (2019) studied this question.
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