Key result
A 25-year-old woman with primary breast angiosarcoma and no previous radiotherapy was treated with a total mastectomy followed by radio-chemotherapy.
Case Report (n=1)
Primary breast angiosarcoma is a rare entity with no standard therapeutic approach, though total mastectomy appears to be the only treatment with proven benefit.
INTRODUCTION: Angiosarcomas of the breast are a rare subtype of sarcomas that frequently are diagnosed after radiation therapy for primary breast cancer. Primary angiosarcomas are rare entities accounting 0.05% of all malignant breast neoplasm. PRESENTATION OF CASE: We report a case of primary angiosarcoma of the breast in a 25 years woman, with no previous radiotherapy, treated with a total mastectomy followed by radio-chemotherapy. DISCUSSION: Total mastectomy appears to be the only treatment known that has proven to benefit these patients. Adjuvant treatment has not proven value up until today. The 5-year disease free survival for grade 1 tumors can be as high as 76%, and up to 15% for grade 3. CONCLUSION: Due to the rarity of these tumors there is no standard therapies approach.
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Iacoponi et al. (2016) conducted a case report in Primary breast angiosarcoma (n=1). Total mastectomy followed by radio-chemotherapy was evaluated. A 25-year-old woman with primary breast angiosarcoma and no previous radiotherapy was treated with a total mastectomy followed by radio-chemotherapy.
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