Key result
Breast cancer radiation therapy linked to fatal bilateral angiosarcoma in a 40-year-old woman.
Case Report (n=1)
No
Breast angiosarcoma is a rare, aggressive tumor with poor prognosis where the main treatment is large surgery with free tumor margins.
Bilateral post-radiation angiosarcoma case adds to sparse reports; leaves open optimal surveillance and margin strategies.
Introduction: Breast angiosarcomas are rare but aggressive malignant endothelial cell tumors. There are two entities: primary angiosarcoma and secondary angiosarcoma to breast irradiation. This neoplasia is characterized by absence of typical features at radiological examination. Case Report: We report a case of a 40-year-old female with a history of invasive ductal breast carcinoma presented with a bilateral breast angiosarcoma. The main treatment is a large surgery with free tumor margins. The role of adjuvant chemotherapy and radiotherapy is still a subject of debate. For inoperable and metastatic disease, chemotherapy is the pillar of treatment. Conclusion: The prognosis of breast angiosarcoma is still poor. Many prospective trials are needed to establish more clear therapeutic strategies.
No takes yet. Share an insight, caveat, or question.
Mouna et al. (2017) conducted a case report in Breast angiosarcoma (n=1). Mastectomy and chemotherapy was evaluated. A 40-year-old woman developed aggressive bilateral breast angiosarcoma following radiation therapy for breast cancer and died despite mastectomy and chemotherapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: