Breast angiosarcoma is a rare and highly aggressive malignancy with a poor prognosis. Arising from endothelial cell lining, it represents approximately 0.04–0.05% of all breast malignancies and less than 1% of all sarcomas. It can be divided into primary and secondary angiosarcoma. Primary angiosarcoma typically affects younger women with no known risk factors, radiation-induced angiosarcoma (RIAS) is classified as secondary angiosarcoma. Breast angiosarcoma is a rare malignant mesenchymal tumour that develops in breast vascular tissue. Diagnosis is often delayed because this condition is rare, and manifests most of the times as a painless lump that grows quickly. Progressive disease can develop distant metastases making the prognosis poor.
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Marzouq et al. (2024) studied this question.
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