Breast Angiosarcoma: Diagnostic Challenges and Management of a Rare Malignancy

Background: Primary angiosarcoma of the breast is an uncommon and aggressive vascular malignancy, representing less than 0.05% of all breast cancers. It often lacks distinct radiological features, which can delay diagnosis. Case Summary: We present the case of a 67-year-old woman with no prior radiotherapy who developed a rapidly enlarging right breast mass. She underwent total mastectomy followed by adjuvant chemo‑radiotherapy. Conclusion: Due to its rarity and variable presentation, primary breast angiosarcoma poses diagnostic and therapeutic challenges. A multidisciplinary approach is essential for optimal patient outcomes.