Etiologic Considerations of Plummer-Vinson (Paterson-Kelly) Syndrome

Article1 November 1958ETIOLOGIC CONSIDERATIONS OF PLUMMER-VINSON (PATERSON-KELLY) SYNDROMEERNEST L. WYNDER, M.D., JEFFREY H. FRYER, M.B., B.S.ERNEST L. WYNDER, M.D., JEFFREY H. FRYER, M.B., B.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-5-1106 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPlummer-Vinson syndrome, as classically described, occurs mostly in women and is characterized by smooth, thin facial skin; a narrow mouth, often termed a "fish-mouth," with a tendency to fissuring at the angles; a smooth tongue; brittle nails that may be spoon-shaped, particularly on the thumb and first three fingers; a past or present history of anemia and dysphagia, often of long duration, and there is also the likelihood of complete edentia. Of these features of the syndrome, only dysphagia is an absolute requirement for diagnosis; furthermore, characteristic anatomic changes in the hypopharynx and upper esophagus must be demonstrated to be...Bibliography1. Paterson DR: A clinical type of dysphagia, J. Laryng. and Otol. 34: 289-291, 1919. CrossrefGoogle Scholar2. Kelly AB: Spasm at entrance to the esophagus, J. Laryng. and Otol. 34: 285-289, 1919. CrossrefGoogle Scholar3. Vinson PP: Hysterical dysphagia, Minnesota Med. 5: 107, 1922. Google Scholar4. Moutier F: La dysphagie sideropenique: du syndrome de Kelly-Paterson (ex-syndrome Plummer-Vinson) au cancer hypopharynge, Arch. d. mal. de l'app. digestif 40: 53-87, 1951. MedlineGoogle Scholar5. MoerschConner HJHM: Hysterical dysphagia, Arch. Otolaryng. 4: 112, 1926. CrossrefGoogle Scholar6. Cameron JA: Dysphagia and anemia, Quart. J. Med. 22: 43, 1928. Google Scholar7. Witts LJ: The syndrome of glossitis, dysphagia and anemia, Guy's Hosp. Rep. 81: 193-204, 1931. 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XXXII. THE EPIDEMIOLOGY OF CANCER*The Paterson-Brown Kelly SyndromeA study of etiological factors in cancer of the esophagus 1 November 1958Volume 49, Issue 5Page: 1106-1128KeywordsAnemiaDysphagiaEpidemiologyEsophagusMouthPreventive medicineRural areasTongue Issue Published: 1 November 1958 PDF downloadLoading ...