Discovery of a New Class of Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B by Biology‐Oriented Synthesis

A biologically relevant collection: The synthesis of a macroline-derived compound collection (see general structural formula) on the basis of the criterion of biological relevance yielded an unprecedented class of inhibitors of the title mycobacterial enzyme, which is a potential target for the development of new antimycobacterial drug candidates.