Why the study?
Does 7.5% hypertonic sodium chloride improve survival and hemodynamics after hemorrhage in a swine model?
Population
Chronically instrumented swine (unanesthetized for the lethal hemorrhage evaluation)
Comparison
7.5% sodium chloride solution vs No treatment, Ringer's lactate infusion, 0.9%…
Design
Preclinical
Authors
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Should not yet alter clinical hemorrhage protocols; hypothesis-generating for 7.5% hypertonic saline in trauma models.
Does 7.5% hypertonic sodium chloride improve survival and hemodynamics after hemorrhage in a swine model?
Resuscitation with low-volume 7.5% hypertonic sodium chloride improves survival and tissue perfusion after severe hemorrhage in a swine model.
Traverso et al. (1987) studied this question.
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