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Summary. The gastric‐secretory excitant from the pyloric mucosa shows the following chemical porperties:— It is soluble in water. The solubility varies with the pH. It is insoluble in ether, acetone, benzene, and absolute and 80% ethyl alcohol. It is stable in weak acid and alkaline solutions. It resists heating in N/10 HCl at 100° C. but is destroyed when heated in N/10 NaOH to this temperature. It is inactivated by pepsin, trypsin (duodenal juice), and ultraviolet light. It dialyses through cellophane. It is precipitated by trichloracetic acid, metaphosphoric acid, NaCl, and acetone.
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Börje Uvnäs (1943) studied this question.
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