Advantage of Anaerobic Conditions in the Highly Enantioselective Synthesis of α,α-Dialkyl-α-Amino Acids by Chiral Phase-Transfer Catalysis

All articles of this category Intervention of the enolate oxidation in the catalytic asymmetric phase-transfer alkylation of protected α -amino acid derivatives under aerobic conditions has been addressed, and anaerobic conditions have been introduced to obtain synthetically satisfactory chemical yields as well as a high level of enantioselectivity. alkylation - anaerobic conditions - chiral phase-transfer catalysis - protected α -amino acid derivatives - oxidation