Answers are grounded in this paper and cite their sources.
Laboratory evaluation demonstrates effective titration of Epstein-Barr virus capsid antibodies using immune adherence hemagglutination, suggesting a practical alternative to immunofluorescence.
The immune adherence hemagglutination assay was found to be as sensitive and specific as the indirect immunofluorescence technique for titration of antibodies to Epstein-Barr virus capsid antigen. Satisfactory virus capsid antigen-specific and negative control antigens for the immune adherence hemagglutination assay were prepared from cell extracts of the Epstein-Barr virus producer P3HR-1 and the Epstein-Barr virus genome-negative BJAB lymphoblastoid cell lines, respectively. As the immune adherence hemagglutination assay can be used to titrate antibodies to both the heterophil antigen of the Paul-Bunnell type and to virus capsid antigen, it offers a promising alternative to the immunofluorescence methods in the serodiagnosis of Epstein-Barr virus infections which can be performed by most diagnostic laboratories.
No takes yet. Share an insight, caveat, or question.
Lennette et al. (1982) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: