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The efficacy of oral prostaglandin E(2) used on a titration basis in association with amniotomy for the induction of labour was investigated in a series of 50 patients. Induction was successful in 29 out of 32 primigravid and 17 out of 18 multigravid patients. The mean induction-delivery intervals in successful cases were 10(1/2) and 6 hours respectively. There were no significant effects on the fetuses.
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Ian Craft (1972) studied this question.
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