Why the study?
Are picornavirus RNA sequences present in the central nervous system tissue of patients with amyotrophic lateral sclerosis compared to controls?
Are picornavirus RNA sequences present in the central nervous system tissue of patients with amyotrophic lateral sclerosis compared to controls?
Picornavirus RNA sequences were rarely detected in the CNS of ALS patients and controls, though prolonged autolysis times may have limited detection sensitivity.
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Picornavirus RNA rarely detected in ALS CNS; leaves open a viral role pending optimized detection methods.
Brahic et al. (1985) studied this question.
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