Why the study?
Does the JCL-trileaflet mechanical heart valve prosthesis (Tricusp) improve hydrodynamic performance compared to commercially available bileaflet valves in an in vitro pulse duplicator model?
Does the JCL-trileaflet mechanical heart valve prosthesis (Tricusp) improve hydrodynamic performance compared to commercially available bileaflet valves in an in vitro pulse duplicator model?
The new Tricusp trileaflet mechanical heart valve demonstrates comparable or superior in vitro hydrodynamic performance to standard bileaflet valves, suggesting potential for clinical application.
Supports further preclinical testing of trileaflet designs; leaves open in vivo durability and clinical translation.
The hydrodynamic performance of a newly developed JCL-trileaflet mechanical heart valve prostheses (Tricusp) was measured and compared with some of the currently most used heart valve prostheses types. All experiments were performed in an electrohydraulic, computer-controlled pulse duplicator simulating the left side of the human circulatory system. Testing conditions were set according to a Food and Drugs Administration interlaboratory comparison protocol, with cardiac outputs 3.0, 4.5, 6.5 or 8.0 l/min and a constant heart rate of 70 beats/min. Mean systolic pressure differences, volume and energy losses, dimensionless pressure losses and energy loss coefficients were calculated from the recorded pressure, volume and flow tracings. The results with the Tricusp valve were found to be as good, or even better than those with the currently most used commercially available bileaflet valves.
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Lentell et al. (1996) studied this question.
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