Saliva was obtained by applying capillary tubes to the mouthparts of the cattle tick, Boophilus microplus (Can.), after the subcuticular injection of pilocarpine hydrochloride. Acid-lipid extracts of this saliva showed prostaglandin (PG)-like activity on bioassay. Chromatographic studies confirmed this activity as being due to PGE 2 . Extracts from homogenates of B. microplus larvae and salivary gland tissue also showed prostaglandin-like activity. A role for PGs in B. microplus feeding mechanisms is discussed.
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Higgs et al. (1976) studied this question.
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