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A direct extraction of the antigen of group A beta-hemolytic streptococci from 373 throat swabs was done with a microtechnique of the nitrous acid extraction-Phadebact coagglutination method. The technique yielded a 96% agreement with the results obtained by a standard throat culture method in which the Phadebact grouping procedure with overnight broth supernatants was employed.
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Slifkin et al. (1982) studied this question.
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