Thiol groups play an essential role in most of the enzymes of pyruvate metabolism In yeast, pyruvate oxidation by living cells is strongly inhibited by thiol reagents such as ethyl iodoacetate or chloroacetophenone, which, never- theless, do not apparently affect pyruvate decarb- oxylation by carboxylase (Stoppani, 1951). These observations have led us to make a detailed study of the role of thiol groups in yeast carboxylase.
No takes yet. Share an insight, caveat, or question.
Stoppani et al. (1953) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: