Why the study?
Does heart rate variability during REM and non-REM sleep differ in patients with vasovagal syncope compared to normal controls?
Population
37 patients with vasovagal syncope (VVS) and 20 normal age-matched controls
Comparison
Polysomnography with 24-hour Holter monitoring… vs Normal age-matched controls
Design
Case-control
Follow-up
24 hours
Authors
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Sympathetic suppression during REM sleep associated with vasovagal syncope; hypothesis-generating and requires prospective validation before clinical use.
Does heart rate variability during REM and non-REM sleep differ in patients with vasovagal syncope compared to normal controls?
Patients with vasovagal syncope exhibit sympathetic suppression during REM sleep compared to healthy controls, suggesting an autonomic abnormality during specific sleep stages.
Cintra et al. (2005) studied this question.
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