The chromatographic and electrophoretic enantiomeric separation and analysis of several clinically used cardiovascular drugs have been reviewed. Several examples of recently reported applications of enantioselective analysis and various cardiovascular agents are presented. Copyright © 1999 John Wiley & Sons, Ltd. Abbreviations used: AEKC affinity electrokinetic chromatography CBH-1 cellobiohydrolase 1 β-CD β-cyclodextrin CE capillary electrophoresis Chiral AGP α1-acid glycoprotein column Chyrosine-A tyrosine-derived CSP CSC (S)-10-camphorsulfonyl CSP — Chiralcel OD cellulose tris(3,5-dimethylphenyl carbamate) chiral stationary phase DDITC (1S,2S)- or (1 R,2R-N-](2-isothiocyanato(cyclohexyl[-(3,5)-dinitrobenzoylamidem GC–MS gas chromatography–mass spectrometry GITC 2,3,4,6-tetra-O-acetyl-β-D-glucosyl isothiocyanate MCF (S)-(−)-menthyl chloroformate MSTFA N-methyl(trimethylsilyl)trifluoroacetamide NAB-C 4-(6-methoxy-2-naphthyl)-2-butyl chloroformate NAP-C (−)-2-(6-methoxy-2-naphthyl)-1-propyl chloroformate NAP-IT (+)-1-(6-methoxy-2-naphthyl)ethyl isothiocyanate PEIC 1-phenylethylisocyanate (R,R)-DACH-DNB CSP (R,R)-dinitrobenzoyl-diaminocyclohexane CSP SFC supercritical fluid chromatography S-NEIC (S)-(−)-1-(1-naphthyl)ethyl isocyanate.
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Bojarşki et al. (1999) studied this question.
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