Translating Results from The Womed Model of Benign Thyroid Disease to A Practical Approach to Treat Fatigue In COVID-19 Patients Based on Combined Supplementation with Magnesium, Selenium, and Coenzyme Q10: A Treatment Strategy against Fatigue

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We describe a small series of patients who were examined at a time post-COVID-19 infection.The main common complaint at presentation was fatigue.Using a previously described and clinically validated examination method based on 3D-Power Doppler sonography of the thyroid, we could identify signs of coenzyme Q 10 (CoQ 10 ) deficiency in these cases.In our previous investigations we have been able to correlate CoQ 10 deficiency with a metabolic switch to glycolysis, i.e. a biochemical process with low ATP production output.Combined supplementation with magnesium, selenomethionine and CoQ 10 improved the clinical condition.Signs of CoQ 10 deficiency persisted in 2 cases where stress situation through workload persisted.Stress is a condition associated with low levels of CoQ 10 .We propose that CoQ 10 deficiency can be involved in the pathogenesis of COVID-19 infection affecting physical performance, and potentially also heart function resulting in fatigue.Experimental and clinical data from the literature on the use of CoQ 10 suggest that this compound should be considered in treatment strategies for COVID-19 patients.