Why the study?
Does the accumulation of risk markers predict sudden death in patients with chronic heart failure?
Population
680 stable patients with chronic heart failure (CHF)
Comparison
Accumulation of 3 or more risk markers vs 2 or fewer risk markers
Design
Cohort
Authors
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May refine sudden death risk stratification in chronic HF; hypothesis-generating and requires prospective validation before guiding therapy.
Does the accumulation of risk markers predict sudden death in patients with chronic heart failure?
The accumulation of three or more specific risk markers is a powerful predictor of sudden death in patients with chronic heart failure, identifying a high-risk cohort with an 11% annual sudden death mortality.
Watanabe et al. (2005) studied this question.
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