Why the study?
Does general anaesthesia with propofol and opioids delay gastric emptying in patients undergoing minor gynaecological surgery compared to controls?
Does general anaesthesia with propofol and opioids delay gastric emptying in patients undergoing minor gynaecological surgery compared to controls?
General anaesthesia with propofol, with or without opioids, significantly delays gastric emptying immediately after minor gynaecological surgery.
Supports caution with early oral intake after minor gynaecological surgery; leaves open generalizability and need for randomized confirmation.
Gastric emptying was measured using the paracetamol absorption method in 30 patients immediately after a general anaesthetic for minor gynaecological surgery and in 10 female controls. Anaesthesia was induced with either propofol alone, propofol and alfentanil (4.5 micrograms.kg-1) or propofol and fentanyl (1.4 micrograms.kg-1) and maintained with intermittent propofol and 66% nitrous oxide in oxygen. Gastric emptying was delayed significantly in all patient groups when compared with volunteers. However, the delay in gastric emptying was similar in the three patient groups.
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Mushambi et al. (1992) studied this question.
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