Alternating VTs with opposite QRS axes can originate from a single focal source in the right bundle branch, which can be successfully mapped and ablated.
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Alternating VTs may share a single right bundle focus amenable to ablation; extends mapping targets but leaves open broader applicability.
Key Teaching Points•Alternating types of ventricular tachycardia (VT) with left bundle branch block pattern and opposite QRS axes at first sight suggest 2 distinct VT sources due to right ventricular (RV) cardiomyopathy.•In this case, a single idiopathic focus originating in the distal right bundle branch close to the septal insertion of the moderator band (MB) and mimicking 2 VTs by alternating exits from the source was confirmed by electroanatomic mapping, pace mapping, and successful ablation.•The MB anatomy and insertion at the medial RV septum likely facilitated alternating inferior and superior activation spreads from the VT source, resulting in entirely opposite vectors of ventricular activation. •Alternating types of ventricular tachycardia (VT) with left bundle branch block pattern and opposite QRS axes at first sight suggest 2 distinct VT sources due to right ventricular (RV) cardiomyopathy.•In this case, a single idiopathic focus originating in the distal right bundle branch close to the septal insertion of the moderator band (MB) and mimicking 2 VTs by alternating exits from the source was confirmed by electroanatomic mapping, pace mapping, and successful ablation.•The MB anatomy and insertion at the medial RV septum likely facilitated alternating inferior and superior activation spreads from the VT source, resulting in entirely opposite vectors of ventricular activation.
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Josiek et al. (2017) studied this question.
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