Why the study?
Does simultaneous intravenous administration of atropine and prostigmine increase the risk of sudden death during general anesthesia?
Does simultaneous intravenous administration of atropine and prostigmine increase the risk of sudden death during general anesthesia?
Answers are grounded in this paper and cite their sources.
Highlights the risk of sudden death due to vagal inhibition when atropine and prostigmine are administered simultaneously intravenously during general anesthesia.
The occurrence of cardiac inhibition during general anesthesia is cited as one of the possible causes of sudden death. The facts concerning the subject are few and it is generally accepted that atropine gives adequate protection. The introduction of the intravenous use of prostigmine as an antidote to curare brings into prominence the question of vagal inhibition during anesthesia, particularly in view of the recent reports of deaths following the simultaneous intravenous admini- stration of atropine and prostigmine
No takes yet. Share an insight, caveat, or question.
Marianne Johnstone (1951) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: