Why the study?
What pre-operative risk factors increase the likelihood of receiving postoperative organ support in patients undergoing colorectal cancer surgery?
What pre-operative risk factors increase the likelihood of receiving postoperative organ support in patients undergoing colorectal cancer surgery?
Nearly 10% of patients undergoing colorectal cancer surgery require postoperative organ support, with heart failure and type II diabetes identified as independent risk factors.
May inform preoperative risk stratification in colorectal cancer surgery; leaves open whether interventions targeting these factors reduce organ support needs.
BACKGROUND: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of organ support. The aim of this study was to identify pre-operative risk factors that increased the likelihood of this occurring. METHODS: This is a retrospective observational study of all 6441 patients who underwent colorectal cancer surgery within the West of Scotland Region between 2005 and 2011. Logistic regression was employed to determine factors associated with receiving postoperative organ support. RESULTS: A total of 610 (9 %) patients received organ support. Multivariate analysis identified age ≥65, male gender, emergency surgery, social deprivation, heart failure and type II diabetes as being independently associated with organ support postoperatively. After adjusting for demographic and clinical factors, patients with metastatic disease appeared less likely to receive organ support (p = 0.012). CONCLUSIONS: Nearly one in ten patients undergoing CRC surgery receive organ support in the post operative period. We identified several risk factors which increase the likelihood of receiving organ support post operatively. This is relevant when consenting patients about the risks of CRC surgery.
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Dale et al. (2016) studied this question.