Nerve growth factor, S-100 protein, CD44, and CD34 have unique expressions in or surrounding eccrine coil but are not found in eccrine duct or apocrine gland. We studied 15 cases of cutaneous cylindroma to see if these antigens are found in this neoplasm. All were found in cylindroma to varying degrees. These results link the histogenesis of cylindroma to the eccrine coil. A unique feature of cylindroma is the large number of prominent dendritic cells most likely representing Langerhans cells that permeate the tumor aggregates.
No takes yet. Share an insight, caveat, or question.
Penneys et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: