Why the study?
Does MCA flow velocity asymmetry predict underlying carotid disease and stroke?
Does MCA flow velocity asymmetry predict underlying carotid disease and stroke?
MCA flow velocity asymmetry >15% on transcranial Doppler is a significant marker for underlying carotid disease and stroke.
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MCA asymmetry on TCD may prompt targeted carotid imaging; leaves open incremental prognostic value beyond standard assessment in observational data.
Utilizing the UIC Vascular Laboratory Registry, we retrospectively analysed the significance of side to side middle cerebral artery (MCA) flow velocity differences. Side to side differences > 15 percent measured by transcranial Doppler were considered asymmetric. Asymmetric subjects had 5 times greater chance of having significant cervical carotid narrowing on either side on Duplex Doppler and a 3.7 times greater chance of having a stroke on brain CT or MRI. MCA flow velocity asymmetry is a marker for underlying carotid disease and stroke.
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Brint et al. (1996) studied this question.
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