Why the study?
Does the logistic EuroSCORE accurately predict long-term survival in patients undergoing primary CABG?
Does the logistic EuroSCORE accurately predict long-term survival in patients undergoing primary CABG?
Logistic EuroSCORE is a reasonable predictor of long-term survival after CABG for scores <5, but its predictive capacity is limited for higher scores due to the omission of factors like LIMA usage, BMI, diabetes, and CKMB.
Answers are grounded in this paper and cite their sources.
Use logistic EuroSCORE cautiously for long-term CABG survival when >5%; leaves open its broad applicability in higher-risk patients.
OBJECTIVES: Coronary artery bypass grafting (CABG) is performed for symptoms and for prognostic reasons. The EuroSCORE is widely utilized as a pre-operative risk prediction tool. We evaluated our long-term survival figures based on EuroSCORE. METHODS: A prospective database was retrospectively analysed and cross correlated with the UK strategic tracking service to evaluate survival after primary CABG. Patients were grouped based on their logistic EuroSCORE 0 to <5, 5 to <10, 10 to <15, 15 to <20, 20 to <25 and ≥25. RESULTS: We analysed 13,337 primary cardiac procedures. A total of 9961 procedures had a logistic EuroSCORE of 0 to <5, 2041 of 5 to <10, 636 of 10 to <15, 281 of 15 to <20, 137 of 20 to <25 and 281≥25. Long-term survival is significantly affected by logistic EuroSCORE, P < 0.001. Patients with a logistic EuroSCORE <5% had significantly better initial survival and a lower rate of death over a 10-year period, P<0.001. Patients with a logistic score over 25 had a significantly worse 5-year survival, P<0.001. Logistic EuroSCORE was poor at predicting survival when >5 and <25. Cox multivariate regression and neuronal network analysis confirmed that the additional factors, diabetes, body mass index (BMI), post-operative myocardial creatinine kinase myocardial isoenzyme (CKMB) and left internal mammary artery (LIMA) usage, which are not incorporated in EuroSCORE significantly predict long-term survival. CONCLUSIONS: Logistic EuroSCORE is a reasonable approximation for long-term survival after CABG, if the score is <5; however, its predictive capacity is limited due to the absence of LIMA usage, BMI, diabetes and CKMB in its calculation, all of which are significant factors affecting long-term survival.
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O’Boyle et al. (2012) studied this question.
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