Key result
Patients undergoing CABG had similar survival to the general Norwegian population, with a 3-year mortality rate of 7.1%, though EuroSCORE overestimated mortality by almost five-fold.
Why the study?
Does coronary artery bypass grafting (CABG) provide survival rates comparable to the general population in patients requiring surgical revascularization?
Cohort (n=1,351)
No
Does coronary artery bypass grafting (CABG) provide survival rates comparable to the general population in patients requiring surgical revascularization?
Patients undergoing CABG have similar short- and intermediate-term survival to the general population, and while EuroSCORE predicts mortality trends well, it overestimates absolute mortality by almost five-fold.
Supports favorable post-CABG survival matching population norms in this cohort; leaves open EuroSCORE recalibration for absolute risk estimates.
OBJECTIVES: Examine short- and intermediate-term survival after coronary artery bypass grafting (CABG) and compare this to survival of the general population and to that predicted by EuroSCORE. DESIGN: One thousand three hundred and fifty one consecutive patients undergoing CABG were prospectively included. Survival status was ascertained through the Norwegian National Registry. RESULTS: Compared to the general population, no statistical significant difference in survival was seen in operated patients. Overall mortality rate was 0.8% after 30 days, 2.8%, 4.0% and 7.1% at one, two and three years, respectively. When patients were divided into four groups according to EuroSCORE, mortality increased significantly with increasing score, as expected. However, EuroSCORE overestimated mortality. CONCLUSION: Patients operated with CABG at our institution have similar survival as in the general Norwegian population. Although overestimating mortality by almost five-fold, we found a strong association between EuroSCORE and short-time survival, and an association between EuroSCORE and intermediate-term survival.
No takes yet. Share an insight, caveat, or question.
Engebretsen et al. (2008) conducted a cohort in Coronary artery disease requiring CABG (n=1,351). Coronary artery bypass grafting (CABG) vs. General Norwegian population was evaluated on Overall mortality at 3 years. Patients undergoing CABG had similar survival to the general Norwegian population, with a 3-year mortality rate of 7.1%, though EuroSCORE overestimated mortality by almost five-fold.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: